The Allotec® Process
After thorough removal of the surrounding soft tissue, fat and cartilage, the tissue is shaped into its final form. In the ultrasound bath, blood, cell and tissue components are washed out, but in particular the fat tissue is removed from the cancellous structure of the bone.
In the purification process with volatile reagents, non-collagenous proteins are denatured, potential viruses inactivated and bacteria killed. In the subsequent oxidative treatment, persistent soluble proteins are denatured and potential antigenicity is eliminated.
Finally, the tissue is lyophilised. In this tissue-preserving drying process, frozen tissue water is sublimated from the solid phase into the gaseous phase. The natural structure of the tissue is preserved. Lyophilisation preserves the structural properties of the tissue, accelerating the incorporation of the graft.1-3
Sterilisation by gamma irradiation ensures a sterility assurance level with a SAL value of 10-6 while maintaining the structural and functional integrity of the material and packaging.